NURS 6501: MIDTERM EXAM: Please contact Assignment Samurai for help with NURS 6501: Midterm Exam or any other assignment. Email: assignmentsamurai@gmail.com       Which endocrine disorder is associated with decreased bone resorption and consequent thickening of the bone (osteosclerosis)? Group of answer choices

• Cushing Syndrome
• Hyperthyroidism
• Diabetes mellitus
• Hypoparathyroidism

  The correct answer is Hypoparathyroidism. Explanation: Hypoparathyroidism is an endocrine disorder where there is insufficient secretion of parathyroid hormone (PTH). PTH is essential for regulating calcium levels in the blood by promoting bone resorption, increasing calcium absorption from the gut, and reducing calcium excretion in the kidneys. When PTH levels are low (as in hypoparathyroidism), there is a decrease in bone resorption, leading to osteosclerosis—a condition characterized by abnormal bone thickening. Here's why the other options are incorrect:

• Cushing Syndrome: This condition involves high levels of cortisol, which typically leads to increased bone resorption and bone loss (osteoporosis), not thickening of the bone.
• Hyperthyroidism: In this condition, elevated thyroid hormone levels lead to increased bone resorption, which can cause thinning of the bones (osteoporosis).
• Diabetes Mellitus: This disorder does not directly cause thickening of the bones, although it can contribute to bone health issues in the long term.

Thus, hypoparathyroidism is the condition that leads to decreased bone resorption and bone thickening (osteosclerosis).