NURS 6501: Final Exam Question 34 / NURS-6501N Advanced Pathophysiology
  NURS 6501: Final Exam: Please contact Assignment Samurai for help with NURS 6501: Final Exam or any other assignment. Email: assignmentsamurai@gmail.com A nurse practitioner is educating a patient about herpes simplex virus (HSV) infections. Which of the following statements accurately describes a unique characteristic of HSV? Group of answer choices
  • HSV primarily causes lesions in the frontotemporal region of the brain.
  • HSV can become latent and reside within nerve ganglia, leading to potential recurrences.
  • HSV infection heals within two to three weeks and never recurs.
  • HSV infection in pregnant women always results in vertical transmission to the newborn.
  The correct answer is: HSV can become latent and reside within nerve ganglia, leading to potential recurrences.   Explanation: A key unique feature of herpes simplex virus (HSV) is its ability to establish latency in sensory nerve ganglia after primary infection, which allows for reactivation and recurrent outbreaks.
  • HSV-1: Typically establishes latency in the trigeminal ganglion (oral herpes).
  • HSV-2: Typically establishes latency in the sacral ganglia (genital herpes).
Why Not the Others?
  • "HSV primarily causes lesions in the frontotemporal region of the brain":
    • While HSV can cause herpes encephalitis (most common in the temporal lobe), this is rare and not a defining feature of typical HSV infections.
  • "HSV infection heals within two to three weeks and never recurs":
    • False—HSV lesions heal, but the virus remains dormant and can reactivate.
  • "HSV infection in pregnant women always results in vertical transmission":
    • False—Transmission risk is highest during primary HSV infection near delivery, but not guaranteed.
Clinical Implications:
  • Antivirals (e.g., acyclovir) can suppress recurrences but do not eliminate latency.
  • Neonatal HSV is a severe complication but preventable with C-section if active lesions are present at delivery.
Thus, latency in nerve ganglia is the most accurate and unique characteristic of HSV.