NURS 6501: Final Exam Question 27/ NURS-6501N Advanced Pathophysiology
  NURS 6501: Final Exam: Please contact Assignment Samurai for help with NURS 6501: Final Exam or any other assignment. Email: assignmentsamurai@gmail.com   A sexually active young adult presents with a clear urethral discharge and dysuria. A Gram-stain of the discharge reveals numerous white blood cells but no organisms. Which organism is most likely responsible for these symptoms? Group of answer choices
  • Mycoplasma genitalium
  • Ureaplasma urealyticum
  • Neisseria gonorrhoeae
  • Chlamydia trachomatis
The correct answer is: Chlamydia trachomatis   Explanation: The patient’s symptoms (clear urethral discharge, dysuria) and Gram stain findings (WBCs but no organisms) are classic for non-gonococcal urethritis (NGU), most commonly caused by:
  • Chlamydia trachomatis (obligate intracellular bacterium, not visible on Gram stain).
  • Mycoplasma genitalium is another cause but is less common than Chlamydia.
Why Not the Others?
  • Neisseria gonorrhoeae:
    • Causes purulent discharge with Gram-negative intracellular diplococci on Gram stain.
  • Ureaplasma urealyticum:
    • A rare cause of NGU but not as common as Chlamydia.
  • Mycoplasma genitalium:
    • Increasingly recognized but still less prevalent than Chlamydia in NGU.
Key Diagnostic Approach:
  • NAAT (PCR) testing is the gold standard to confirm Chlamydia or Mycoplasma.
  • Empirical treatment for NGU:
    • Azithromycin 1g single dose (covers Chlamydia) or
    • Doxycycline 100mg BID x 7 days (also covers Mycoplasma).
Thus, Chlamydia trachomatis is the most likely cause.